ABSTRACT
For the evaluation on the efficacy of activated charcoal as an antidote in acute diquat poisoning, the adsorption characteristics of diquat in distilled water and in physiological saline solution were investigated.<BR>The amount of diquat adsorbed onto activated charcoal in physiological saline solution was larger than that in distilled water. The enhancing effect of sodium chloride on diquat removal by activated charcoal was observed.<BR>The adsorption rate of diquat onto activated charcoal was also enhanced by the addition of saline. The correlations between the adsorptivity for diquat and properties of activated charcoal were not significant.<BR>These results suggest that the increase of adsorptivity of activated charcoal for diquat might be due to the increase in electrostatic interaction between the surface on which an electrical double layer was formed by saline and diquat.
ABSTRACT
The effect of daily physical activity on the serum lipid level was examined. This study consisted of two parts, an epidemiological study and a laboratory study.<BR>In the epidemiological study, we investigated the relationship between serum lipids and energy expenditure in young adults females. Significant correlations were found between energy expenditure/body weight and the levels of serum HDL-cholesterol and serum triglyceride, and atherogenic index.<BR>In the laboratory study, we examined the effects of exercise on the serum lipid level. Groups of subjects took part in the programs of physical activity of two different intensities for 6 weeks, and their serum lipid levels before and after these programs were compared. Exercise regimens of increasing intensity caused a significant mean increase in the serum HDL-cholesterol level. However, these regimens did not cause any significant change in serum total cholesterol and serum triglyceride values.<BR>These results suggest that doing even light exercise on a regular basis is effective in producing an optimum serum lipid pattern in young adult females.
ABSTRACT
In search of a better primary treatment of acute boric acid poisoning, the adsorption capacity of boric acid onto activated carbon as an antidote was investigated <I>in vitro.</I><BR>Wide differences in the amount of boric acid adsorbed were recognized depending on individual activated carbons. In order to elucidate the dominant factor in boric acid adsorption, correlations between the properties of activated carbon and the amounts of boric acid adsorbed are discussed. A significant correlation was recognized between the surface pH of activated carbon and the amount of boric acid adsorbed in low equilibrium concentration. It is assumed that the surface pH of activated carbon is a chief factor affecting the amount of boric acid adsorbed.
ABSTRACT
The relationship between serum creatine phosphokinase (CPK) activity and labor strength was examined.<BR>Our epidemiological study showed thar the serum CPK activity in a group of men who worked over ten hours was significantly higher than that in the other groups who worked less than ten hours. In women, the serum CPK activity in a group who worked over seven hours was significantly higher than that in the other groups. The serum CPK activity in fishermen was significantly higher than that in those engaged in other than fishery.<BR>In a laboratory study, test subjects were divided into 3 groups to perform 3 types (30%, 50%, 70% of VO<SUB>2max</SUB>) of exercise for 6 weeks. A rise in the serum CPK activity was noted in every group during exercise. The mean increase for these groups were 44.0 %, 48.1 % and 67.9 %, respectively.
ABSTRACT
In this study, the effects of excessive iodine intake on free thyroixine index (FTI) were studied, and the results are presented in the following.<BR>FTI tended to decrease during the basal diet period without wakame seaweed and the decrease tended to continue further during the periods of TEST 1 (wakame seweed 10g/day) and TEST 2 (wakame seaweed 20g/day). The trend changed in the period of TEST 3 (wakame seaweed 40g/day), and FTI rose slightly. When the basal diet was resumed after completion of experimental diets, the level returned to the base line levels measured before the beginning of the experiment.
ABSTRACT
The effects of large doses of vitamin C on serum alkaline phosphatase activity were examined in six young healthy volunteers. The experiment lasted 30 days. The results obtained were as follows.:<BR>he mean basal AL-P level in the six subjects was 5.9±2.3 K-A unit. Upon administration of 1g/day of vitamin C, the values increased to the mean of 6.9±2.6 K-A unit, while after a dose of 10g/day, the mean came to 6.8±2.1 K-A unit. All the subjects showed increased AL-P serum levels relative to the control period.
ABSTRACT
The purpose of this study is to make clear a comprehensive relationship between serum transaminase activity and food intake pattern. A total of 146 young male student participated in the study.<BR>The results of the survey were as follows:<BR>1) The first factor (Fl) was a“animal-related food factor”. The second factor (F2) was considered to be a“rice versus noodles factor”. The third (F3), fourth (F4), fifth (F5) and sixth (F6) factor could not be explained simply in terms of their factor.<BR>2) Significantly negative correlations were observed between SGOT and the factor scores of Fl (r=-0.256, p<0.01), SGPT and the factor scores of Fl (r=-0.243, p<0.01), and SGPT and factor scores of F2 (r=-0.195, p<0.05), but not between SGOT or SGPT and other factors.
ABSTRACT
Relationship between serum OCT activity and nutrient intake pattern were investigated in 90 young adults. Applying multiple regression and factor analysis, we found the following results:<BR>1) Multiple regression analysis showed that the variables which correlated best with the serum OCT activity were dietary intakes of the energy, fat and vitamin C.<BR>2) In the factor analysis, no significant correlation was found between serum OCT and food intake pattern.
ABSTRACT
The effects of the food intake pattern on the activity and fraction pattern of serum γ-glutamyl transpeptidase (γ-GTP) were examined in 257 healthy Japanese men.<BR>Applying the technique of factor analysis to the food intake data, the following three factors were extracted. The first factor (F1): meats, eggs, and vegetables had a highly positive factor loading. The second factor (F2): wheat had a highly positive factor loading, while rice had a highly negative factor loading. This factor was considered to be a “wheat versus rice factor”. The third factor (F3) could not be explained simply in terms of its factor. The scores of the first two factors for the 257 subjects were calculated.<BR>Significantly negative correlations were observed between the percentage of GT<SUB>1</SUB> fraction and the factor score of F1 (r=-0.230, p<0.01), between the percentage of GT<SUB>1</SUB> fraction and the factor score of F2 (r=-0.187, p<0.01). The total serum γ-GTP activity was not correlated with the factor score. These results suggested that the percentage of GT<SUB>1</SUB> fraction is influenced by the pattern of food intake.
ABSTRACT
The effects of the serum vitamin C levels on the activity and isozyme pattern of serum lactate dehydrogenase (LDH) in males and females in their middle and old age were examined.<BR>There was no siginificant correlation among the total serum, LDH activity and serum vitamin C levels in the 87 male and 83 female ranging from 45 to 84 years of age. However, high inverse correlations were found among the percentage of LDH-4 and LDH-5 and serum vitamin C levels all of age groups (45-59 years of age group, 60-69 years of age group and over 70 years of age group) of males and females.<BR>These results suggest that the percentage of LDH-4 and LDH-5 are influenced by the vitamin C intake in males and females in their middle and old age.
ABSTRACT
For the preservation of health in rural areas, this paper reports on the variation of human serum lipids by intaking lentinus edodes.<BR>Serum lipids levels showed no significant change by intaking lentinus edodes that amounts of 20, 40 and 60g per day each for 5 days. From data of correlationship between serum lipid levels and nutrition intake of experimental diet, it was recognized that high-density-lipoprotein cholesterol level was directly proportional to carbohydrate-fat ratio significantly (p< 0.02), and was inversely proportional to fat intake, fat-protein ratio and carbohydrate-protein ratio significantly (p< 0.05), respectively. Triglycerides level was inversely proportional to protein intake significantly (p< 0.05).<BR>These results concluded that the decrease of serum cholesterol level by intaking of lentinus edodes in healthy young men whose serum cholesterol levels were in normal range was not recognized.
ABSTRACT
This survey was conducted in a local city, Tokushima for its 23 administrative sections, which were classified into rural, non-rural and mixed districts based on the data related to agriculture. Complaints of public nuisances in these districts have been examined and the following findings have been obtained.<BR>1. Complaints about water pollution and offensive odor in the rural district and those about offensive odor and noise in the mixed district have been raised more often, respectively. While, in the non-rural district more complaints about noise have been raised. Thus, it is recognized that possible pollution phenomena vary depending on regional patterns.<BR>2. In time-serial comparison between the first half (1977-1980) and the second half (1981-1984) of survey period, it is found that total complaints of public nuisances have been reduced and the complaints in the rural district have been increased for all the types excepting dust. Therefore, it is suggested that regional environment in suburban farm villages has been deteriorating.
ABSTRACT
Relationship between SGOT/SGPT ratio and energy intake were investigated in 1030 subjects (373 males, 657 females). These figures were taken from epidemiological survey of the Tokushima prefecture from 1975 to 1980.<BR>The results of the survey were as follows.<BR>1) Energy intakes in reversal group (SGOT/SGPT <1) was higher than that in nromal group (SGOT/SGPT >1).<BR>2) Body weight in reversal group was higher than that in normal group except young woman (18-39 years).<BR>3) Incidence of reversal of SGOT/SGPT ratio showed increasing values as energy intakes levels increased.<BR>It is possible to conclude from the results that SGOT/SGPT ratio was affected by energy intakes.
ABSTRACT
This paper reports the changes in the activity and isozyme pattern of serum LDH in healthy young men given a low protein diet (0.73-0.75/kg body weight; 40-50g/day) for 21 days.<BR>Serum total LDH activity showed no significant change in eight healthy young volunteers who received low protein diet for 21 days. However, the percentages of LDH-5 and LDH-4 increased significantly (P<0.01) from basal levels of 5.9±2.3 and 7.1±1.4 to 10.6±2.9% and 10.1±0.9%, respectively on day 14.<BR>These results suggest that measurements of the percentages of LDH-4 and LDH-5 isozymes can be used to evaluate the protein intake, but serum LDH activity cannot be used as an index of nutrition.
ABSTRACT
The purpose of the present paper is to explore the relationships between the activity and fraction ratio of serum γ-GTP and the dietary intake of nutrients through three groups (lean, normal and overweight) by Broca's index. Broca's index in each groups was under 89 for the lean group, from 90to 109 for the normal group and over 110 for the overweight group. The subjects of study were 249 young healthy men except alcoholic.<BR>Results of the survey were as follows:<BR>1) There were statistically significant correlation between serum total γ-GTP activity in normal group and vitamin C intake (P<0.05).<BR>2) High negative correlations were observed between the fraction ratio of serum γ-GTP (1) and the vitamin B 1 intake (P<0.01), between the fraction ratio of serum γ-GTP (1) and vitamin C intake (P<0.01), and between the fraction ratio of serum γ-GTP (1) and the protein intake/kg of body weight (P<0.01) in the lean group. High negative correlations were observed between the fraction ratio of serum γ-GTP (1) and the protein intake (P<0.01), between the fraction ratio of serum y -GTP (1) and the vitamin B 1 intake (P<0.01), between the fraction ratio of serum γ-GTP (1) and vitamin C intake (P<0.01), and between the fraction ratio of serum γ-GTP (1) and the protein intake/kg of body weight (P<0.01) in the normal group. High negative correlation was observed between the fraction ratio of serum γ-GTP (1) and the vitamin C intake (P<0.01) in the overweight group.<BR>3) Multiple regression analysis showed that the variables which correlated best with the fraction ratio of serum γ-GTP (1) were dietary intakes of the energy, the vitamin C and the protein intake/kg of body weight in the lean group. The fraction ratio of serum γ-GTP (1) related to the vitamin C intake and the protein intake/kg of body weight in the normal group. In the overweight group, the fraction ratio of serum γ-GTP (1) related to the vitamin C intake and the animal protein intake.
ABSTRACT
The purpose of this study is to make clear comprehensive relationship between Thymol turbidity test values (TTT) and the dietary intakes of nutrients. The subjects of this study were 287 young healthy people in Tokushima prefecture.<BR>The results of the survey were as follows:<BR>1) In males, multiple regression analysis showed that variables which correlated best with the TTT values were dietary intakes of sugar energy and vegetable protein aged 30-49 years, and dietary intakes of animal fat and energy aged 50-69 years.<BR>2) In females, multiple regression analysis showed that variables which correlated best with TTT values were dietary intakes of animal protein and vegetable fat aged 50 69 years, but there were no statistically significant correlation between TTT values and the dietary intakes of nutrients aged 30-49 years.
ABSTRACT
The purpose of this study is to make clear a comprehensive relationship between two groups of serum enzyme activity and nutrient intakes. The first group of measurement include serum GOT, GPT, ALP activity and the second group of measurements include protein, fat, carbohydorate, vitamin A, B1, B2, C, animal protein, animal fat, age, and weight.<BR>These figures are taken from the epidemiological survey of Tokushima prefecture, including 252 males and 383 females, investigated from 1975 to 1980.<BR>Appling the canonical correlation analysis, we found the following results.<BR>1) In male, only two canonical correlations were statistically significant. The serum GOT and GPT activity related to body weight, further serum GOT activity was effected quality of food intakes.<BR>2) In Female, three canonical correlations were statistically significant. Both serum GOT and GPT activity related to protein intakes. High correlations were observed between serum GOT activty and vitamin B1, between serum GPT activity and vitamin C, between serum ALP activity and age.
ABSTRACT
The purpose of this study is to make clear a comprehensive relationship between two groups of blood properties and nutrient intakes. The first group of measurement include hemoglobin contents, hematocrits and blood specific gravity and the second group of measurements includ energy, protein, fat, carbohydorate, vitamin A, B<SUB>1</SUB>, B<SUB>2</SUB>, C, animal protein, animal fat, iron, animal iron and age.<BR>These figures are taken from the epidemiological survey of Tokushima prefecture, including 301 males and 379 females, investigated from 1975 to 1980.<BR>Appling the canonical correlation analysis, we found the following results.<BR>1) In male, only canonical correlations were statistically significant. The hematocrit related strongly to carbohydorate, animal protein, fat intakes and age.<BR>2) In female, only canonical correlations were statisticall significant. Both hemoglobin contents and blood specific gravity effected carbohydorate and energy intakes.